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32

NCCN Guidelines for Patients

®

:

Rectal Cancer, Version 1.2017

What to expect

Chemotherapy regimens used for rectal cancer

are listed in

Guide 2

. Sometimes, only one

drug is used. Other times, more than one drug is

used because drugs differ in the way they work.

A combination regimen is the use of two or more

chemotherapy drugs.

Most chemotherapy drugs for rectal cancer are

liquids that are injected into your body. They are

almost always injected into a vein. A slow injection

is called an infusion. Bolus injections are fast. Only

capecitabine and trifluridine/tipiracil are in pill form.

Chemotherapy will enter your bloodstream. Once in

the bloodstream, it can travel throughout your body

to treat cancer. Doctors use the term “systemic”

3

Overview of cancer treatments

Chemotherapy

Guide 2. Chemotherapy types

Single agent or combination

Generic name

Brand name

5-FU/LV

5-FU = fluorouracil

LV = leucovorin*

Capecitabine

Capecitabine

Xeloda

®

CAPEOX

CAPE = capecitabine

Xeloda

®

OX = oxaliplatin

Eloxatin

®

FLOX

F = fluorouracil

L = leucovorin*

OX = oxaliplatin

Eloxatin

®

Floxuridine

Floxuridine

Fluorouracil

Fluorouracil

FOLFIRI

FOL = leucovorin*

F = fluorouracil

IRI = irinotecan

Camptosar

®

FOLFOX

FOL = leucovorin*

F = fluorouracil

OX = oxaliplatin

Eloxatin

®

FOLFOXIRI

FOL = leucovorin*

F = fluorouracil

OX = oxaliplatin

Eloxatin

®

IRI = irinotecan

Camptosar

®

Irinotecan

Irinotecan

Camptosar

®

Trifluridine + tipiracil

Trifluridine + tipiracil

Lonsurf

®

*Levoleucovorin can be used instead of leucovorin