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NCCN Guidelines for Patients



Rectal Cancer, Version 1.2017


Metastatic disease

Part 5 is a treatment guide for rectal

cancer that has spread to the liver or

lungs but not elsewhere. Treatment

options are partly based on whether

the metastasis was found at diagnosis

or recurrence. Treatment for other

metastases is discussed in Part 6.

The spread of cancer to distant sites—metastatic

disease—occurs in at least half of people with

colorectal cancer. Colorectal cancer most often

spreads to the liver. Among every 100 people with

colorectal cancer, 20 to 34 people will have liver

metastases at diagnosis. Most options for liver

metastases also apply to lung metastases.