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NCCN Guidelines for Patients


Soft Tissue Sarcoma, Version 1.2014


The third option for stage IIA is to have radiation

therapy followed by surgery. Radiation therapy before

surgery may reduce the chances of the cancer

returning. It may also improve how well your limb

works after surgery. However, radiation will likely

slow healing of the surgical wound. Before having

surgery, you may get another imaging test. This test

will assess the tumor and rule out metastatic disease.

After surgery, you may receive a radiation boost.

There are four options for stages IIB and III. All four

include surgery to remove the tumor. Your lymph

nodes should also be removed if the cancer is

stage III. The cancer has spread to the lymph nodes.

Surgery followed by radiation therapy is strongly

recommended. Other options include radiation

therapy, chemoradiation, or chemotherapy before

surgery. A radiation boost may follow surgery that was

preceded by radiation therapy. A boost may help if the

cancer wasn’t fully removed or cancer was found in

the margins.

After surgery for IIB or III disease, you may receive

chemotherapy. However, the research on its benefits

at this point of care is limited. It is not clear if

chemotherapy is helpful. Joining a clinical trial that is

testing chemotherapy may be a good option.


Sarcomas in limbs, outer trunk, head, or neck Stages II and III sarcoma