NCCN Guidelines for Patients
Soft Tissue Sarcoma, Version 1.2014
The third option for stage IIA is to have radiation
therapy followed by surgery. Radiation therapy before
surgery may reduce the chances of the cancer
returning. It may also improve how well your limb
works after surgery. However, radiation will likely
slow healing of the surgical wound. Before having
surgery, you may get another imaging test. This test
will assess the tumor and rule out metastatic disease.
After surgery, you may receive a radiation boost.
There are four options for stages IIB and III. All four
include surgery to remove the tumor. Your lymph
nodes should also be removed if the cancer is
stage III. The cancer has spread to the lymph nodes.
Surgery followed by radiation therapy is strongly
recommended. Other options include radiation
therapy, chemoradiation, or chemotherapy before
surgery. A radiation boost may follow surgery that was
preceded by radiation therapy. A boost may help if the
cancer wasn’t fully removed or cancer was found in
After surgery for IIB or III disease, you may receive
chemotherapy. However, the research on its benefits
at this point of care is limited. It is not clear if
chemotherapy is helpful. Joining a clinical trial that is
testing chemotherapy may be a good option.
Sarcomas in limbs, outer trunk, head, or neck Stages II and III sarcoma