NCCN Guidelines for Patients
Soft Tissue Sarcoma, Version 1.2014
For widespread cancer growth, options are to
increase the dose of imatinib or start taking sunitinib.
After the new treatment, your doctors will assess if
the treatment is working with CT or MRI. PET may be
used if CT or MRI results are unclear.
Joining a clinical trial is highly encouraged. You’ll
likely receive the best management of care. Ask your
treatment team if there are clinical trials you can join.
lists treatment options if the cancer
keeps growing while taking imatinib or sunitinib.
There are four treatment options. Taking regorafenib
is strongly supported. You may also join a clinical trial
or start alternate treatment. However, less research
has been done to know if the alternate treatments will
be helpful. The fourth option is to receive supportive
care to relieve any discomfort you may have. As
part of supportive care, you should continue to take
imatinib or another drug even if your tumor is growing.
The tumor will grow more slowly on some treatment
than on none.
Gastrointestinal stromal tumors Treatment after progression