NCCN Guidelines for Patients
Soft Tissue Sarcoma, Version 1.2014
Learning that you have cancer can
be overwhelming. This chapter briefly
describes what sarcoma is and the
types of treatment. These basics may
help you cope and better understand
Parts 2 through 6.
What is soft tissue sarcoma?
Sarcomas are a large but rare group of cancers.
Sarcomas start in cells that make up bones or soft
tissue. Soft tissue supports, connects, and surrounds
parts of your body. Soft tissue includes fat, muscles,
nerves, tendons, and blood and lymph vessels.
Soft tissue sarcomas are more common than bone
There are over 50 types of soft tissue sarcoma.
These types differ by the type of soft tissue. They also
differ by the type and shape of cells and how much
the cells look like normal cells. A list of soft tissue
sarcomas can be found in the
. The most
common types are:
• Undifferentiated pleomorphic sarcoma,
• GISTs (
• Synovial sarcoma, and
• Malignant peripheral nerve sheath tumors.
Soft tissue sarcomas can occur anywhere in the body.
The most common place is in the arms and legs.
About 43 out of 100 (43%) sarcomas occur in the
6 What is soft tissue sarcoma?
8 Local treatments
10 Drug treatments
12 Clinical trials