NCCN Guidelines for Patients
Breast Cancer - Carcinoma in Situ
, Version 1.2016
All biopsy samples must be viewed by a pathologist.
The type and extent of the disease will be confirmed.
Among women with LCIS, over half have LCIS in
more than one lobule. Sometimes, both LCIS and
breast cancer are found. The breast cancer may be
confined to or have spread beyond the breast ducts.
If an invasive breast cancer is found, read the NCCN
patient book related to the cancer stage.
The pathology results will be recorded in a report. It’s
a good idea to get a copy of your pathology report. It’s
used to plan treatment.
Although LCIS increases your risk for breast cancer,
you may not need risk-reduction treatment. There
are many other risk factors to consider. One very
important risk factor is if any of your blood relatives
have had breast or ovarian cancer, especially at a
Using your medical and family history, your doctor
will tell you, in general, how likely you are to get
breast cancer. If there’s a history of cancer in your
family, you should be referred for genetic counseling.
A genetic counselor is an expert in gene mutations
related to cancer. The counselor can better determine
your risk for breast cancer.
The counselor may suggest testing for mutations in
genes that are related to breast cancer and passed
down in families. Such mutations can occur in
genes help to
prevent tumor growth. Women with
gene mutations are more likely to have breast
and ovarian cancer than other women.
Based on all risk factors, your genetic counselor will
advise if risk-reduction treatment would be helpful.
However, it’s your choice whether to start treatment.
Risk-reduction treatment is briefly described next.
Changes in your lifestyle may reduce your chances of
developing breast cancer. Examples are eating more
healthfully, limiting alcohol use, exercising more, and
achieving a healthy body weight. Your doctor can
suggest lifestyle changes that are specific to you.
Female hormones help some breast cancers grow.
Endocrine therapy includes treatments that stop
cancer growth caused by hormones. Endocrine
therapy is sometimes called hormone therapy and