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NCCN Guidelines for Patients


Breast Cancer - Carcinoma in Situ

(stage 0)

, Version 1.2016



estrogen receptor

A protein inside of cells that binds with estrogen.

estrogen receptor–negative

Cancer cells that don’t use estrogen to grow.

estrogen receptor–positive

Cancer cells that use estrogen to grow.

excisional biopsy

Surgery that removes an entire tumor to test for cancer cells.

external beam radiation therapy (EBRT)

Treatment with radiation received from a machine outside

the body.

fine-needle aspiration

Removal of a small tissue sample with a very thin needle.


Coded instructions in cells for making new cells and

controlling how cells behave.

general anesthesia

A controlled loss of wakefulness from drugs.

genetic counseling

Discussion with a health expert about the risk for a disease

caused by changes in genes.

hereditary breast cancer

Breast cancer that was likely caused by abnormal genes

passed down from parent to child.


A health condition in which muscles weaken or tear allowing

organs or tissue to extend out.


Chemical in the body that activates cells or organs.

hot flashes

A health condition of intense body heat and sweat for short


immunohistochemistry (IHC)

A lab test of cancer cells to find specific cell traits involved in

abnormal cell growth.

in situ

In its original place – cancer cells have not spread from

where they first formed.

incisional biopsy

A minor surgery that removes a tissue sample from a tumor.

internal radiation

Treatment with radiation received from an object placed near

or in the tumor.

invasive breast cancer

Cancer cells have grown into the supporting tissue of the


lobular carcinoma in situ (LCIS)

Abnormal cells within the breast lobules only.


A gland in the breast that makes breast milk.

local anesthesia

A controlled loss of feeling in a small area of the body from



Surgery to remove a breast lump and some normal tissue

around it.


A clear fluid containing white blood cells.

lymph node

Small groups of special disease-fighting cells located

throughout the body.

magnetic resonance imaging (MRI)

A test that uses radio waves and powerful magnets to make

pictures of the insides of the body.


A picture of the insides of the breast that is made by an x-ray



Surgery to remove the whole breast.

medical history

All health events and medications taken to date.

multiple-catheter boost radiation

Use of multiple small tubes to place radioactive seeds in your

body for treatment.


An abnormal change in the instructions in cells for making

and controlling cells.