NCCN Guidelines for Patients
Breast Cancer - Early-Stage
(STAGES I AND II)
, Version 1.2016
Breast cancer basics
• Inside of women’s breasts are lobules, ducts,
and stroma. Lobules are structures that make
breast milk. Ducts carry breast milk from the
lobules to the nipple. Stroma is a soft tissue
that surrounds the lobules and ducts.
• Breast cancer often starts in the lobules or
ducts and then grows into the stroma.
• Breast cancer can spread outside the breast
to vital organs through lymph or blood.
• Breast cancer that is stage I or II has grown
into the stroma but not into the breast skin or
chest wall. It has not spread to distant sites.
• Clinical trials are the treatment option that is
preferred by NCCN experts. Other options
involve surgery, chemotherapy, HER2
inhibitors, radiation therapy, endocrine
therapy, follow-up care, and recurrence
treatment. Parts 2 through 8 present what
your options may be.