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41

NCCN Guidelines for Patients

®

Breast Cancer - Early-Stage

(STAGES I AND II)

, Version 1.2016

As shown in

Figure 4.1

, some chemotherapy drugs

work when cells are in an active growth phase. During

the active growth phase, cells grow and divide to

form a new cell. Chemotherapy drugs that disrupt

the growth phase work well for cancer cells that are

growing and dividing quickly. Other chemotherapy

drugs work whether cells are in a growth or resting

phase. Chemotherapy can kill both cancer and

normal cells. Do not receive chemotherapy if you are

in the first three months of pregnancy.

4

Chemotherapy and HER2 inhibitors Overview

Figure 4.1 Cell phases

A cell goes through many changes to divide into two cells. Science has grouped

these changes into 7 main phases. There may be another phase of rest, too. Some

chemotherapy drugs work in any phase. Other chemotherapy drugs work in one or

two growth phases.

Chemotherapy may work in some or all phases of cell division