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50

NCCN Guidelines for Patients

®

Breast Cancer - Early-Stage

(STAGES I AND II)

, Version 1.2016

Chart 4.4 Preferred regimens*

Preferred Regimen

Schedule

Total time

Dose-dense AC

Four 14-day cycles

4 months

then paclitaxel

Four 14-day cycles

Dose-dense AC

Four 14-day cycles

5 months

then paclitaxel

Twelve 7-day cycles

TC

Four 21-day cycles

3 months

4

Chemotherapy and HER2 inhibitors Regimens: HER-2 negative cancer

*Preferred and other regimens are based on how well they work, side effects, and treatment schedules.

Abbreviations

AC = doxorubicin + cyclophosphamide

CEF = cyclophosphamide + epirubicin + fluorouracil

CMF = cyclophosphamide + methotrexate + fluorouracil

EC = epirubicin + cyclophosphamide

FAC = fluorouracil + doxorubicin + cyclophosphamide

FEC = fluorouracil + epirubicin + cyclophosphamide

TAC = docetaxel + doxorubicin + cyclophosphamide

TC = docetaxel + cyclophosphamide

Regimens: HER-2 negative cancer