NCCN Guidelines for Patients
Breast Cancer - Early-Stage
(STAGES I AND II)
, Version 1.2016
Breast cancer recurrence
Treatment options are based in part on where the
recurrence is. A local recurrence is breast cancer that
returned within a breast or within the chest wall near
to where a breast is or was. A regional recurrence
includes breast cancer that returned in lymph nodes
near to the breast area. These lymph nodes include
those near your armpit (axillary lymph nodes), below
your collarbone (infraclavicular lymph nodes), above
your collarbone (supraclavicular lymph nodes), and
near to your breastbone (internal mammary nodes).
Treatment options for recurrences are explained next.
Doctors use the term “systemic” when talking about
a cancer treatment for the whole body. Systemic
treatment for breast cancer recurrences includes
chemotherapy, chemotherapy with HER2 inhibitors,
and endocrine therapy.
lists the treatment options for a local
recurrence based on your prior treatment. If you had
breast-conserving therapy, a total mastectomy is
advised. You may also have an axillary lymph node
dissection if not done before. Systemic treatment may
be part of your treatment, too.
If previously treated with mastectomy alone, you
may have surgery to remove the cancer. Afterward,
radiation therapy to the chest wall and the lymph
nodes around your collarbone is advised. Systemic
treatment may be added.
You may have had a mastectomy, axillary lymph
node dissection, and radiation therapy. In this case,
the cancer should be removed by surgery if possible.
Systemic treatment may be added.
lists the treatment options for a recurrence
in your lymph nodes. The cancer may have also
returned in or near a breast. Treatment options are
based on which lymph nodes have cancer.
If cancer is found in your axillary lymph nodes,
these lymph nodes should be removed if possible.
Radiation therapy is also advised. Radiation sites
include your chest wall, near your armpit (axilla), and
the lymph nodes around your collarbone. You may
receive systemic treatment, too.
Radiation therapy without surgery is advised for
the return of cancer in supraclavicular or internal
mammary nodes. For a supraclavicular recurrence,
radiation sites include your chest wall and lymph
nodes around the collarbone. For an internal
mammary recurrence, radiation sites include your
chest wall, internal mammary nodes, and nodes
around the collarbone. You may receive systemic