Table of Contents Table of Contents
Previous Page  17 / 88 Next Page
Show Menu
Previous Page 17 / 88 Next Page
Page Background


NCCN Guidelines for Patients



Breast Cancer – Locally Advanced (STAGE III)

Version 1.2017


Breast cancer basics


To join, you’ll need to review and sign an informed

consent form. This form describes the study in detail.

The study’s risks and benefits should be described

and may include others than those described above.

Ask your treatment team if there is an open clinical

trial that you can join. There may be clinical trials

where you’re getting treatment or at other treatment

centers nearby. You can also find clinical trials

through the websites listed in Part 9.




Inside of women’s breasts are lobules, ducts,

and stroma. Lobules are structures that make

breast milk. Ducts carry breast milk from the

lobules to the nipple. Stroma is a soft tissue

that surrounds the lobules and ducts.



Breast cancer often starts in the milk ducts or

lobules and then spreads into the stroma.



Breast cancer can spread outside the breast

through lymph or blood.



Stage III breast cancers are divided into three

groups. Stage IIIA cancers do not involve the

breast skin or chest wall but have spread into

nearby lymph nodes. Stage IIIB cancers do

involve the breast skin, chest wall, or both.

Stage IIIC cancers have spread to a great

extent within nearby lymph nodes.



Treatment for stage III breast cancer has many

parts. Common treatments are chemotherapy,

surgery, radiation therapy, and endocrine

therapy. Not everyone receives the same

chemotherapy or surgery. The order of some

treatments may differ, too.



Clinical trials give people access to new tests

and treatments that they otherwise can’t

receive. If proven to work well, they may be

approved in time by the FDA.