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NCCN Guidelines for Patients



Breast Cancer – Locally Advanced (STAGE III)

Version 1.2017

Not all breast cancers are the same. Your

cancer doctor will want to learn all about

the cancer you have. Part 2 describes the

tests used to learn about breast cancer.

Based on the test results, your treatment

can be tailored to you. This is called

personalized medicine.

Medical history

Your medical history includes any health events and

medicines you’ve taken in your life. Your cancer

doctor will want to know about illnesses, breast

biopsies, prior treatment with radiation, and if you are

pregnant. It may help to make a list of old and new

medications while at home to bring to your doctor’s


Breast cancer and other health conditions can run in

families. Thus, your cancer doctor will ask about the

medical history of your blood relatives. Hereditary

breast cancers are due to abnormal genes that

were passed down from a parent to a child. They

are not common. About 1 out of 10 breast cancers

are hereditary. Read the section called



to learn more.

A medical history is needed for treatment planning.


Guide 1

for a complete list of care that is

advised prior to treatment. Some women do not need

every test or service listed.

Guide 1. Health care before cancer treatment

Main tests and services

Other care that may be useful

Medical history

Chest diagnostic CT scan with contrast

Physical exam

Abdomen ± pelvis diagnostic scans (CT or MRI with


Diagnostic bilateral mammogram

Bone scan or sodium fluoride PET/CT

Breast ultrasound if needed

FDG PET/CT sometimes

Breast MRI sometimes

Complete blood count


Comprehensive metabolic panel

Hormone receptor test on cancer cells

HER2 test on cancer cells

Genetic counseling if you may have hereditary

breast cancer

Fertility counseling if you can have babies

Distress screening


Treatment planning

Medical history