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Version 1.2017


NCCN Guidelines for Patients



Breast Cancer – Locally Advanced (STAGE III)

How to use this book

Who should read this book?

This book is about treatment for stage III breast

cancer. These cancers are carcinomas of the breast.

Inflammatory breast cancer is not included.

Almost all breast cancers occur in women. As such,

most of this book is written with women in mind.

However, men are treated like women except where


Patients and those who support them—caregivers,

family, and friends—may find the book helpful. It is

a good starting point to learn what your options may


Are the book chapters in a

certain order?

The book chapters follow a common treatment

pathway. Starting with

Part 1

may be helpful. It

explains what stage III breast cancer is. Also,

common treatment pathways are discussed.

Part 2

lists what health care is needed before

treatment. Some types of health care help your

doctors plan treatment. Other health care can

address health issues beyond cancer treatment.

Parts 3 through 8

describes the common treatment

types. Options for treatment are also included. Tips

for talking and deciding your options with your doctor

are presented in

Part 9


Does this book include all


This book includes information for many people.

Your treatment team can point out what applies to

you. They can also give you more information. While

reading, make a list of questions to ask your doctors.

The treatment options are based on science and

the experience of NCCN experts. However, their

recommendations may not be right for you. Your

doctors may suggest other options based on your

health and other factors. If other options are given,

ask your treatment team questions.

Help! What do the words


In this book, many medical words are included.

These are words that your treatment team may say

to you. Most of these words may be new to you. It

may be a lot to learn.

Don’t be discouraged as you read. Keep reading and

review the information. Ask your treatment team to

explain a word or phrase that you do not understand.

Words that you may not know are defined in the text

or in the


. Acronyms are also defined when

first used and in the


. Acronyms are short

words formed from the first letters of several words.

One example is DNA for