NCCN Guidelines for Patients
Stomach Cancer, Version 1.2016
Preparing for treatment
As part of the genetic risk assessment, your doctor
will ask about the medical history of your blood
relatives. It’s important to know who in your family has
had what diseases and at what ages the diseases
started. Your doctor may ask about the health of
your children and grandchildren, your siblings, your
parents and their siblings, and your grandparents.
No one in your family may have had stomach or
a related cancer. However, you still may have an
inherited syndrome that increased your chances of
getting stomach cancer. A syndrome is a group of
signs or symptoms that occur together and suggest
the presence of or risk for a disease. Inherited
syndromes related to stomach cancer include:
• HDGC (
• Lynch syndrome [HNPCC (
• Juvenile polyposis syndrome,
• Peutz-Jeghers syndrome,
• Classic or attenuated FAP (
• Ataxia- telangiectasia,
• Bloom syndrome,
• Hereditary breast and ovarian cancer
• Li-Fraumeni syndrome, and
• Xeroderma pigmentosum.
If your doctor thinks you have hereditary stomach
cancer, you should be referred to a genetic counselor.
A genetic counselor can talk with you about getting
tested for syndromes related to stomach cancer. To
be tested, you must provide a sample of blood. Using
the sample, a pathologist can test your genes for
abnormal changes that cause these syndromes.
For some syndromes, there may be health care
related to cancer that you can receive. Your doctor
may advise regular testing to screen for cancers.
Examples include breast and colon cancer screening.
There may also be treatments that can prevent
Doctors often perform a physical exam along with
taking a medical history. A physical exam is a study of
your body for signs of disease. During this exam, your
doctor will listen to your lungs, heart, and gut.
Your doctor will also look at and feel parts of your
body. This is done to see if organs are of normal size,
are soft or hard, or cause pain when touched. Cancer
and other health conditions can cause organs to
become enlarged and hard.
A CBC (
ount) gives important
information about the parts of blood. One example
is the number of white blood cells, red blood cells,
and platelets. Your blood counts may be low because
the cancer has spread into your bones, the cancer
is causing bleeding, or because of another health
Comprehensive chemistry profile
Chemicals in your blood come from your liver, bone,
and other organs. A comprehensive chemistry profile
assesses if the chemicals in your blood are too low
or high. Abnormal levels can be caused by spread of
cancer or by other diseases.