NCCN Guidelines for Patients
Waldenström’s Macroglobulinemia, Version 1.2017
If a stem cell transplant is an option for you, you will
get those drugs that are non-stem cell toxic. Any
primary treatment listed in
is an option for
people who have already been treated for WM. You
can also consider a clinical trial.
The treatment, drugs, or combination of drugs listed
Guides 4 and 7
are not in any specific order.
They are options for your doctors to use when
considering your next steps. Your doctor will base
your next treatment, whether it is the 2
, or 4
drug, on many factors. The decision will be based on
things specific to you. He or she will also consider
how you handled the other treatment and how the
cancer is responding.
Your next steps will also depend on whether the
cancer is gone, stable, or growing. You can still get
treatment when the cancer is stable. You can get it
when you have no symptoms but had a very good
partial, partial, or minor response to treatment.
For example, it is recommended that rituximab be
given for maintenance. This is called maintenance
treatment. The goal of this treatment is to keep things
Follow-up care is needed after any cancer treatment
is finished. Follow-up care includes a medical history,
physical exam, lab tests, and imaging tests. During
this time, you will have more than one doctor’s visit
to monitor your health. If the cancer re-appears,
a biopsy can be done to confirm there’s cancer. If
cancer is present, your doctor will try the drugs listed
or recommend a clinical trial.
Discuss and decide on a treatment plan with
Your doctor may begin with plasmapheresis.
You can get this treatment before
chemotherapy, targeted therapy, or
You should get primary treatment if you have
symptoms of WM.
If needed, you can have further treatment after
When your treatment is finished, testing will be
done to check treatment results.
Follow-up care is needed after any cancer
treatment is finished. Follow-up care includes
a medical history, physical exam, lab tests, and