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NCCN Guidelines for Patients



Waldenström’s Macroglobulinemia, Version 1.2017


immune system

The body’s natural defense against illness.


A protein made by white blood cells that helps fight off

infection. Also called an antibody.

immunohistochemistry (IHC)

A test of cancer cells to find specific cell traits involved in

abnormal cell growth.


A type of drug that modifies some parts of the body’s

disease-fighting system.


Organ that removes waste from the blood and helps to

digest food.

local anesthesia

A controlled loss of feeling in a small area of the body

caused by drugs.


A clear fluid containing white blood cells.

lymph node

Small groups of special disease-fighting cells located

throughout the body.

lymph vessel

Tube-shaped ducts that carry lymph throughout the body.

lymphatic system

A network in the body that collects and transports a fluid

(lymph) and fights germs.


A type of white blood cell that helps protect the body from



Cancer that begins in white blood cells called lymphocytes

that are within the lymphatic system.

lymphoplasmacytic cells

Cells that have features of both lymphocytes and plasma


magnetic resonance imaging (MRI)

A test that uses radio waves and powerful magnets to make

pictures of the insides of the body.


The spread of cancer cells from the first tumor to another

body part.

medical history

All health events and medications taken to date.

monoclonal antibody

Man-made antibodies that attach proteins on cancer cells.


A doctor who’s an expert in testing cells to find disease.

physical exam

A review of the body by a health expert for signs of disease.

positron emission tomography (PET)

A test that uses radioactive material to see the shape and

function of body parts.

regional anesthesia

A type of drug used for short-term loss of feeling or

awareness in a part of the body without loss of wakefulness.


A drug that helps a person to relax or go to sleep.

side effect

An unplanned physical or emotional response to treatment.


An organ to the left of the stomach that helps protect the

body from disease.

stem cell transplant

A cancer treatment that destroys bone marrow then

replaces it by adding healthy blood stem cells.


A drug used to reduce redness, swelling, and pain, but also

to kill cancer cells.

targeted therapy

Drugs that stop the growth process that is specific to cancer



One of three types of a white blood cell called a lymphocyte.


A gland located in the throat, just beneath the voice box.