National Comprehensive Cancer Network

About The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)
Development and Update of the NCCN Guidelines
Recent Updates to NCCN Guidelines®
NCCN Guidelines Panels-Meeting Schedule
NCCN Categories of Evidence and Consensus
NCCN Categories of Preference
NCCN Guidelines® Steering Committee
Transparency: Process and Recommendations
Submission Request to the NCCN Guidelines Panels
Submission Request History
NCCN Compendium®
About the NCCN Compendium®
NCCN Compendium® Chapters By Disease
Subscribe to the NCCN Compendium
No Longer Recommended Uses
NCCN Framework for Resource Stratification of NCCN Guidelines
(NCCN Framework™)

NCCN Guidelines® & Clinical Resources

About the NCCN Drugs & Biologics Compendium (NCCN Compendium®)

The NCCN Drugs & Biologics Compendium (NCCN Compendium®) lists appropriate uses of agents as defined in and derived from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). As such, the uses listed in the NCCN Compendium® are based upon the evaluation of evidence from scientific literature, integrated with expert judgment in a consensus-driven process. The NCCN Compendium is indexed by drug or biological agent whereas the NCCN Guidelines® are indexed by disease. The NCCN Compendium identifies the pharmacologic characteristics of each drug or biological and includes information on route of administration, as well as the recommended uses in specific diseases. The indicated uses are categorized in a systematic approach that describes the type of evidence available for and the degree of consensus underlying each recommendation. All recommendations (at all category levels) in the NCCN Compendium constitute appropriate, medically-necessary care.

The accelerating pace and productivity of biomedical research, the resultant advances in therapeutic approaches, and the exigencies of serious and life-threatening illnesses present clinical professionals with both significant challenges and opportunities in the selection of treatment regimens for patients with cancer. NCCN is committed to providing sound, scientific recommendations for the appropriate management of a wide range of oncologic conditions. The NCCN Compendium is part of a series of evaluative information products intended to optimize the clinical decision-making process with a view toward improving the care available to patients. The NCCN Compendium contains authoritative, scientifically derived information designed to support decision-making about the appropriate use of drug and biologic therapy in patients with cancer.

Clinical professionals should apply independent medical judgment in their decisions about treatment that meets the clinical characteristics and needs of individual patients with cancer. Also note that the NCCN Compendium's listings represent the conclusions of the NCCN Guideline Panels as of the date of finalization of the relevant NCCN Guideline. NCCN Guidelines are updated continuously.

The NCCN Compendium is updated in conjunction with the NCCN Guidelines on a continual basis. The latest NCCN Guidelines and Compendium updates can be accessed at

Share Your Feedback

NCCN is interested in working with all constituencies in the cancer care delivery system. We encourage you, as a colleague, to provide input as to how the NCCN can enhance the utility and user friendliness of our information products. Please contact us at with your questions, concerns, or comments.