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NCCN Guidelines®

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NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) are posted with the latest update date and version number.

New! NCCN Guidelines® User System (GUS™) - Access an interactive version of the NCCN Guidelines with enhanced interfacing and functionality. NCCN is launching GUS™ with the following NCCN Guidelines: Cancer- and Chemotherapy-Induced Anemia, Chronic Myelogenous Leukemia, Multiple Myeloma, Prostate Cancer, and Systemic Light Chain Amyloidosis .

NCCN Mobile Applications - Access the NCCN Guidelines anywhere and at anytime through free NCCN Guidelines mobile apps for iPhone and Android.

The NCCN Guidelines are copyrighted by the NCCN. All rights reserved. NCCN Guidelines and illustrations (including algorithms) may not be reproduced in any form for any purpose without the express written permission of the NCCN. Permissions Requests Section

View the NCCN Guidelines Panel Members individual disclosures

NCCN Guidelines for Treatment of Cancer by Site

NCCN Guidelines for Detection, Prevention, & Risk Reduction

NCCN Guidelines for Supportive Care

NCCN Guidelines for Patients™

NCCN Guidelines for Treatment of Cancer by Site

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Acute Myeloid Leukemia You Must Login First to Access Physician Guideline CME

Anal Carcinoma You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

Bladder Cancer You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

  • Bladder Cancer
  • Upper Tract Tumors
  • Urothelial Carcinoma of the Prostate

Bone Cancer You Must Login First to Access Physician Guideline

  • Chondrosarcoma
  • Ewing's Sarcoma
  • Osteosarcoma

Breast Cancer You Must Login First to Access Physician GuidelineAccess the Patient Guidelines CME You Must Login First to Access Physician Guideline

  • Noninvasive
  • Invasive
  • Phyllodes Tumor
  • Paget’s Disease
  • Breast Cancer During Pregnancy
  • Inflammatory Breast Cancer

Cancer of Unknown Primary (See Occult Primary)

Central Nervous System Cancers You Must Login First to Access Physician Guideline

  • Adult Low-Grade Infiltrative Supratentorial Astrocytoma/Oligodendroglioma (excluding pilocytic astrocytoma)
  • Anaplastic Gliomas/Glioblastoma
  • Adult Intracranial Ependymoma
  • Adult Medulloblastoma and Supratentorial PNET
  • Primary CNS Lymphoma
  • Primary Spinal Cord Tumors
  • Meningiomas
  • Limited (1-3) Metastatic Lesions
  • Multiple (>3) Metastatic Lesions
  • Leptomeningeal Metastases
  • Metastatic Spine Tumors

Cervical Cancer You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Chronic Myelogenous Leukemia You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline Access the Patient Guidelines CME You Must Login First to Access Physician Guideline Pocket Guidelines


Colon/Rectal Cancer

    Colon Cancer You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

    Rectal Cancer You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

Esophageal Cancer You Must Login First to Access Physician Guideline CME

Fallopian Tube Cancer (See Ovarian Cancer)

Gastric Cancer You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

Head and Neck Cancers You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

  • Cancer of the Lip
  • Cancer of the Oral Cavity
  • Cancer of the Oropharynx
  • Cancer of the Hypopharynx
  • Cancer of the Nasopharynx
  • Cancer of the Glottic Larynx
  • Cancer of the Supraglottic Larynx
  • Ethmoid Sinus Tumors
  • Maxillary Sinus Tumors
  • Unresectable/Recurrent/Persistent Head and Neck Cancer
  • Occult Primary
  • Salivary Gland Tumors
  • Mucosal Melanoma

Hepatobiliary Cancers You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

  • Hepatocellular Carcinoma
  • Gallbladder Cancer
  • Intrahepatic Cholangiocarcinoma
  • Extrahepatic Cholangiocarcinoma

Hodgkin Lymphoma You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Kidney Cancer You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

Malignant Pleural Mesothelioma You Must Login First to Access Physician Guideline

Melanoma You Must Login First to Access Physician Guideline Access the Patient Guidelines CME Pocket Guidelines


Multiple Myeloma/Other Plasma Cell Neoplasms

    Multiple Myeloma You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline Access the Patient Guidelines CME

    Systemic Light Chain Amyloidosis You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

    Waldenström's Macroglobulinemia / Lymphoplasmacytic Lymphoma You Must Login First to Access Physician Guideline


Myelodysplastic Syndromes You Must Login First to Access Physician Guideline

Neuroendocrine Tumors You Must Login First to Access Physician Guideline Pocket Guidelines

  • Carcinoid Tumors
  • Islet Cell Tumors (Pancreatic Endocrine Tumors)
  • Neuroendocrine Unknown Primary
  • Adrenal Gland Tumors
  • Pheochromocytoma
  • Poorly Differentiated (High Grade or Anaplastic)/Small Cell
  • Multiple Endocrine Neoplasia, Type 1
  • Multiple Endocrine Neoplasia, Type 2

Non-Hodgkin's Lymphomas You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline

  • Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
  • Follicular Lymphoma
  • Marginal Zone Lymphoma
  • Mantle Cell Lymphoma
  • Diffuse Large B-Cell Lymphoma
  • Burkitt Lymphoma
  • Lymphoblastic Lymphoma
  • AIDS-Related B-Cell Lymphoma
  • Primary Cutaneous B-Cell Lymphoma
  • Peripheral T-Cell Lymphoma
  • Mycosis Fungoides/Sézary Syndrome
  • Adult T-Cell Leukemia/Lymphoma
  • Extranodal NK/T- Cell Lymphoma, nasal type
  • Post-Transplant Lymphoproliferative Disorders
  • T-Cell Prolymphocytic Leukemia
  • Hairy Cell Leukemia

Non-Melanoma Skin Cancers

    Basal and Squamous Cell Skin Cancers You Must Login First to Access Physician Guideline

    Dermatofibrosarcoma Protuberans You Must Login First to Access Physician Guideline

    Merkel Cell Carcinoma You Must Login First to Access Physician Guideline


Non-Small Cell Lung Cancer You Must Login First to Access Physician Guideline Access the Patient Guidelines CME You Must Login First to Access Physician Guideline

Occult Primary (Cancer of Unknown Primary) You Must Login First to Access Physician Guideline

Ovarian Cancer You Must Login First to Access Physician Guideline Access the Patient Guidelines CME You Must Login First to Access Physician Guideline

  • Epithelial Ovarian Cancer (including Fallopian Tube Cancer and Primary Peritoneal Cancer)
  • Borderline Epithelial Ovarian Cancer (Low Malignant Potential)
  • Less Common Ovarian Histologies

Pancreatic Adenocarcinoma You Must Login First to Access Physician Guideline CME You Must Login First to Access Physician Guideline


Primary Peritoneal Cancer (See Ovarian Cancer)

Prostate Cancer You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline Access the Patient Guidelines CME You Must Login First to Access Physician Guideline

Small Cell Lung Cancer You Must Login First to Access Physician Guideline

  • Small Cell Lung Cancer
  • Lung Neuroendocrine Tumors

Soft Tissue Sarcoma You Must Login First to Access Physician Guideline CME

  • Extremity
  • Retroperitoneal/Intra-Abdominal
  • Gastrointestinal Stromal Tumors (GIST)
  • Desmoid Tumors

Testicular Cancer You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Thymomas and Thymic Carcinomas You Must Login First to Access Physician Guideline

Thyroid Carcinoma You Must Login First to Access Physician Guideline

  • Nodule Evaluation
  • Papillary Carcinoma
  • Follicular Carcinoma
  • Hürthle Cell Neoplasm
  • Medullary Carcinoma
  • Anaplastic Carcinoma

Uterine Neoplasms You Must Login First to Access Physician Guideline

  • Endometrial Cancer
  • Uterine Sarcoma

NCCN Guidelines for Detection, Prevention, & Risk Reduction

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Breast Cancer Risk Reduction You Must Login First to Access Physician Guideline

Breast Cancer Screening and Diagnosis You Must Login First to Access Physician Guideline

Cervical Cancer Screening You Must Login First to Access Physician Guideline

Colorectal Cancer Screening You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Genetic/Familial High-Risk Assessment: Breast and Ovarian You Must Login First to Access Physician Guideline

  • Breast and/or Ovarian Genetic Assessment
  • Hereditary Breast and/or Ovarian Cancer
  • Li-Fraumeni Syndrome
  • Cowden Syndrome

Lung Cancer Screening You Must Login First to Access Physician Guideline

Prostate Cancer Early Detection You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

NCCN Guidelines for Supportive Care

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Adult Cancer Pain You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Antiemesis You Must Login First to Access Physician Guideline Pocket Guidelines

Cancer- and Chemotherapy-Induced Anemia You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Cancer-Related Fatigue You Must Login First to Access Physician Guideline

Distress Management You Must Login First to Access Physician Guideline

Myeloid Growth Factors You Must Login First to Access Physician Guideline CME

Palliative Care You Must Login First to Access Physician Guideline You Must Login First to Access Physician Guideline

Prevention and Treatment of Cancer-Related Infections You Must Login First to Access Physician Guideline CME Pocket Guidelines

Senior Adult Oncology You Must Login First to Access Physician Guideline

Venous Thromboembolic Disease You Must Login First to Access Physician Guideline CME

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Disclaimer
The NCCN Guidelines are a statement of consensus of the authors regarding their views of currently accepted approaches to cancer treatment.  The recommendations regarding the uses and indications in the NCCN Compendium have been derived directly from the NCCN Guidelines.  The NCCN Compendium represents neither an all-inclusive listing of every drug and biologic nor every appropriate use and indication for drugs and biologics.  The NCCN Templates are peer reviewed statements of consensus of their authors derived from the NCCN Guidelines for the conditions the NCCN Templates address.  The NCCN Templates are not exhaustive and do not represent the full spectrum of care or treatment options described in the NCCN Guidelines or the NCCN Compendium or include all appropriate approaches or combinations of drugs or biologics for the treatment of cancer.  A NCCN Template does not constitute an order.

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