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Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Ampullary Adenocarcinoma Anal Carcinoma Basal Cell Skin Cancer B-Cell Lymphomas Biliary Tract Cancers Bladder Cancer Bone Cancer Breast Cancer Castleman Disease Central Nervous System Cancers Cervical Cancer Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Chronic Myeloid Leukemia Colon Cancer Dermatofibrosarcoma Protuberans Esophageal and Esophagogastric Junction Cancers Gastric Cancer Gastrointestinal Stromal Tumors Gestational Trophoblastic Neoplasia Hairy Cell Leukemia Head and Neck Cancers

Hepatobiliary Cancers Hepatocellular Carcinoma Histiocytic Neoplasms Hodgkin Lymphoma Kaposi Sarcoma Kidney Cancer Melanoma: Cutaneous Melanoma: Uveal Merkel Cell Carcinoma Mesothelioma: Peritoneal Mesothelioma: Pleural Multiple Myeloma Myelodysplastic Syndromes Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions Myeloproliferative Neoplasms Neuroblastoma Neuroendocrine and Adrenal Tumors Non-Small Cell Lung Cancer Occult Primary Ovarian Cancer/Fallopian Tube Cancer/Primary Peritoneal Cancer Pancreatic Adenocarcinoma Pediatric Acute Lymphoblastic Leukemia Pediatric Aggressive Mature B-Cell Lymphomas

Pediatric Central Nervous System Cancers Pediatric Hodgkin Lymphoma Penile Cancer Primary Cutaneous Lymphomas Prostate Cancer Rectal Cancer Small Bowel Adenocarcinoma Small Cell Lung Cancer Soft Tissue Sarcoma Squamous Cell Skin Cancer Systemic Light Chain Amyloidosis Systemic Mastocytosis T-Cell Lymphomas Testicular Cancer Thymomas and Thymic Carcinomas Thyroid Carcinoma Uterine Neoplasms Vaginal Cancer Vulvar Cancer Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma Wilms Tumor (Nephroblastoma)

Breast Cancer Risk Reduction Breast Cancer Screening and Diagnosis Colorectal Cancer Screening

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Distress During Cancer Care Esophageal Cancer Fatigue and Cancer Follicular Lymphoma Gallbladder and Bile Duct Cancers Gastrointestinal Stromal Tumors (GIST) Genetic Testing for Hereditary Breast, Ovarian, Pancreatic, and Prostate Cancers Graft-Versus-Host Disease Hodgkin Lymphoma in Adults Hodgkin Lymphoma in Children Immunotherapy Side Effects: CAR T-Cell Therapy Immunotherapy Side Effects: Immune Checkpoint Inhibitors Kidney Cancer Liver Cancer Lung Cancer Screening Mantle Cell Lymphoma Marginal Zone Lymphomas Melanoma Mouth Cancer Multiple Myeloma Myelodysplastic Syndromes Myeloproliferative Neoplasms Nasopharyngeal Cancer Nausea and Vomiting Neuroendocrine Tumors

Non-Small Cell Lung Cancer - Early and Locally Advanced Non-Small Cell Lung Cancer - Metastatic Ovarian Cancer Palliative Care Pancreatic Cancer Peripheral T-Cell Lymphoma Pleural Mesothelioma Primary Central Nervous System Lymphoma Prostate Cancer: Advanced Stage Prostate Cancer: Early Stage Quitting Smoking Rectal Cancer Small Bowel Adenocarcinoma Small Cell Lung Cancer Soft Tissue Sarcoma Squamous Cell Skin Cancer Stomach Cancer Survivorship Care for Cancer-Related Late and Long-Term Effects Survivorship Care for Healthy Living Systemic Mastocytosis Throat Cancer Thyroid Cancer Uterine Cancer Waldenström Macroglobulinemia

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Rectal Cancer

Guidelines

NCCN Guidelines Version 2.2025

- Rectal Cancer

Guidelines Navigator

NCCN Guidelines Navigator™ Version 2.2025 (NEW!)
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NCCN Guidelines in Practice™

Earn CME/CE and MOC credits for using the NCCN Guidelines to research your patient care decisions and clinical questions by clicking here.

Evidence Blocks

NCCN Guidelines with Evidence Blocks Version 2.2025

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Basic Framework (English) Version 2.2024
Core Framework (English) Version 2.2024
Enhanced Framework (English) Version 2.2024

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Rectal Cancer-English Version 2024

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NCCN Guidelines® Insights - Rectal Cancer, Version 3.2024
Recorded Presentation from the NCCN Pharmacy Updates: Advances in Neoadjuvant Treatment Options in Locally Advanced and Metastatic Rectal Cancer with Deficient Mismatch Repair
Recorded Presentation from Optimizing Patient Outcomes - Beyond the Package Insert: Appropriate Interpretation of Testing Results for Targeted Therapy Selection

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English (European/Poland) Version 4.2024

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English (Africa) Version 3.2022

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