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NCCN Content in Health Information Technologies

The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of 27 of the world's leading cancer centers working together to improve the quality, effectiveness and efficiency of cancer care. In furtherance of such purposes, at significant time and expense, the NCCN has developed proprietary content for the provision of cancer care, including without limitation, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), the NCCN Drugs & Biologics Compendium (NCCN Compendium®), the NCCN Chemotherapy Order Templates (NCCN Templates®), and the NCCN Guidelines for Patients®, which are collectively referred to as NCCN Content.

NCCN provides the NCCN Content to hospitals, physicians and other parties and is continuously updating and improving these materials. Please note that the NCCN Content is a valuable asset of NCCN and is protected by copyright, trademark, and other proprietary rights owned by the NCCN. NCCN regularly licenses users of the NCCN Content and does not permit commercial use of the NCCN Content without a license agreement between the user and the NCCN.

NCCN works with organizations through permissions and licensing arrangements to permit the use of NCCN Content in commercial products, including Health Information Technologies (HIT). The organizations listed below are official licensees of NCCN Content for use in HIT. NCCN works to inform and regularly notifies these organizations of updates to the NCCN Content contained in these technologies so as to ensure that the NCCN Content represented in the tools is up-to-date and consistent with what is published on

HIT tools that include the NCCN Guidelines®, NCCN Compendium®, NCCN Biomarkers Compendium™, and NCCN Templates®

IBM Watson is a cognitive technology that processes information more like a human than a computer— by understanding natural language, generating hypotheses based on evidence and learning as it goes.


Private payers and the Centers for Medicare and Medicaid Services (CMS) are increasingly interested in evidence demonstrating greater consistency of cancer care and predictability of costs. Value Pathways powered by NCCN, only available through Clear Value Plus software, aim to help oncologists provide the highest quality treatment to their patients and efficiently document delivery of consistent, evidence-based care.

HIT tools that include the NCCN Compendium®

McKesson’s InterQual® Criteria are evidence-based decision support products that help payer and provider organizations share a common language when determining the right care at the right place and the right time for individuals, driving optimal financial and medical outcomes. InterQual Criteria include inpatient and outpatient levels of care, behavioral health, imaging, procedures, specialty drugs, molecular diagnostics and retrospective monitoring.

A point-of-care enhanced oncology benefit management solution that enables health plans, employers and other payers to support their physicians with the robust clinical resources needed to deliver quality care. New Century Health is an official licensee of the NCCN Compendium®. NCCN supports the development and widespread use of the NCCN Compendium® and has collaborated with New Century Health for communication of this important information.

HIT tools that include the NCCN Imaging AUC™

To learn more about the NCCN Imaging AUC™ click here

National Decision Support Company provides enterprise wide Clinical Decision Support (CDS) solutions that enable more efficient and appropriate care, improve population health, and save money. Our technology platform converts published guidelines from credible, compliant content sources into actionable decision support criteria delivered directly into the EMR workflow. The NCCN Guidelines® enable NDSC’s CareSelect Imaging solution to provide comprehensive CDS coverage for diagnostic imaging. For more information, visit

A point-of-care enhanced oncology benefit management solution that enables health plans, employers and other payers to support their physicians with the robust clinical resources needed to deliver quality care. New Century Health is an official licensee of the NCCN Compendium®. NCCN supports the development and widespread use of the NCCN Compendium® and has collaborated with New Century Health for communication of this important information.

HIT tools that integrate the NCCN Templates®

Epic is an official licensee of the NCCN Chemotherapy Order Templates (NCCN Templates®) and NCCN is collaborating with Epic to integrate NCCN Templates® into Beacon as protocols. This collaboration will provide improved access to evidence-based medicine and standardized care in chemotherapy ordering. The NCCN collaboration with Epic will streamline the Beacon protocol build process so Epic community members will be able to save time by taking advantage of the NCCN Templates® already configured in their software. This integration is scheduled to be available 3rd Quarter 2015.

Flatiron Health helps the oncology community deliver better, more efficient care by powering an innovative platform to address today’s healthcare challenges. The Flatiron Health OncologyCloud platform includes the industry-leading electronic medical record for oncology, advanced analytics, patient portal, and integrated billing management. Backed by Google Ventures, First Round Capital, LabCorp and others, Flatiron’s industry-first technology platform and integrated suite of products deliver comprehensive support for cancer care providers and life science companies.

HIT tools that utilize the NCCN Guidelines®, NCCN Compendium®, and NCCN Biomarkers Compendium® as a reference


American Health Holding is a URAC-accredited, national medical management company providing health care cost savings through flexible solutions, clinical expertise and leading technology. For more than 20 years, the company has helped ensure quality and appropriate care for millions of members through programs including Utilization Management, Case Management, Disease Management, Maternity Management, 24/7 Physician Consultations, Medical Transportation, and Bill Audit Services.

HIT tools that utilize the NCCN Guidelines® and the NCCN Compendium® as a reference


eviCore healthcare offers proven, diversified medical benefit management solutions that help clients reduce costs while increasing quality of care for their members. The company provides these solutions to managed care organizations and risk-bearing provider organizations serving commercial, Medicare and Medicaid populations. Powered by a team of specialized medical professional resources, extensive evidence-based guidelines and advanced technologies, the company supports clients by ensuring the right evidence-based care is delivered at the right time to the right patient at the right site of care.

At Genospace, our mission is to deliver the platform that makes biomedical data useful and usable by everyone. Genospace has built a comprehensive platform for precision medicine to enable interpretation, analysis, reporting and collaboration on high-dimensional genomic and other biomedical data. With specific applications supporting research, development, pathology and clinical care, many of the most advanced precision medicine organizations are powered by Genospace. Please visit for more information.

Hines and Associates, an independent URAC accredited organization, has been providing best in class medical management for over 25 years. Services include utilization management, disease management, and specialty case management for employer groups, TPAs, Welfare Funds, brokers, consultants, MGUs and carriers. Our oncology team consists of actively practicing oncologists, radiation oncologists, interventional radiologists, medical social workers, certified dietitians, and nurses with clinical expertise in adult or pediatric oncology for solid organ or hematologic malignancies. Being independent of providers, networks, or payers assures that Hines has no conflict of interest when supporting quality, best practice oncology care.

INTERLINK owns and operates Centers of Excellence networks used by health plans all across the nation. Our CancerCARE program promotes National Comprehensive Cancer Network® (NCCN®) Member Institutions in our CancerCOE Network and provides clients with model benefit language which ties benefit reimbursement to NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) compliance. INTERLINK Care Management is an official NCCN® licensee which enables our clients to incorporate our CancerCARE benefit language into the plan Summary of Benefits. Few plan documents have cancer specific instructions for members, so CancerCARE provides benefit language, monitors NCCN Guidelines® compliance, and promotes access to CancerCOE Centers for complicated care. CancerCARE monitors all plan cancer care through its Triage Center, which provides early detection and distribution of evidence-based treatment guidelines. CancerCARE benefit language is required to access this program. This program uses our CancerCOE, TransplantCOE and Pathology/DiagnositicCOE networks.

To learn more, visit


MolecularHealth ( uses advanced information technologies to sift through huge volumes of genetic and molecular test findings in a fraction of the time needed for current manual analysis, delivering on the promise of personalized, precision medicine.

We translate this analysis into actionable information that doctors and their patients can use to make informed decisions about cancer care, supporting the best and safest treatment options for each patient. 

MolecularHealth puts the person into personalized medicine.


Optum is a leading information and technology-enabled health services business dedicated to helping make the health system work better for everyone. With more than 35,000 people worldwide, Optum delivers intelligent, integrated solutions that modernize the health system and help to improve overall population health.


PierianDx enables health systems, academic medical centers and commercial labs to deliver patient-specific diagnosis and treatments based on an individual’s DNA. In use since 2011, and regularly enhanced with new patient, clinical and research data, PierianDx’s proprietary Clinical Genomicist Workstation provides clinical labs more streamlined and accurate analysis, interpretation, and reporting needed to accelerate their personalized medicine programs. 

HIT tools that utilize the NCCN Guidelines® and the NCCN Templates® as a reference

Zynx Health is the market leader in providing evidence-based clinical decision support (CDS) solutions proven to measurably improve the quality, safety, and efficiency of patient care. Thousands of hospital organizations and providers trust Zynx Health's suite of customized services and online solutions to reduce care gaps, standardize care, and advance clinical and financial outcomes across the care continuum. Zynx Health is an official NCCN licensee, providing direct access to guidelines as a reference for the provision of cancer care within evidence-based CDS solutions.

HIT tools that utilize the NCCN Guidelines® as a reference

Active Health

ActiveHealth Management is a leading provider of health management services, including disease management, clinical decision support and personal health records. ActiveHealth’s health management solutions are powered by CareEngine® System, which uses advanced clinical analytics to help identify opportunities to improve health for more than 22 million people nationwide. ActiveHealth is honored to be recognized as an official NCCN Licensee. Incorporation of the NCCN Guidelines® in ActiveHealth solutions ensures the appropriate treatments and care guidelines are being referenced.


Active Health

Ambry Genetics is a privately-held healthcare company with the most comprehensive suite of genetic testing solutions for inherited and non-inherited diseases. Since 1999, Ambry has tested nearly one million patient samples benefiting 94% of all U.S. patients covered by public and private insurers. Ambry is dedicated to scientific collaboration by offering its rapidly growing database of anonymized genomic data (variant frequencies) free to the global medical research community to fulfill the promise of the human genome to cure or manage all human disease. Ambry is dedicated to the belief that human health should not be patented or owned, and genomic data should be freely shared so we can try to understand all human disease.

Founded in July 2013, Color Genomics’ goal is to democratize access to genetic information. The Color Test is physician ordered, analyzes 19-genes closely associated with breast and ovarian cancer including BRCA1 and BRCA2, and offers complimentary board-certified genetic counseling for clients and healthcare providers. Headquartered in Burlingame, CA, Color Genomics is privately held and backed by Khosla Ventures, Formation 8 and several leading angel investors. To learn more about Color, follow Color on Twitter @ColorGenomics or Facebook at and visit

DNA Direct was founded in 2005 to address the growing need for genetic expertise and guidance across the healthcare continuum. It was born out of a deep passion and belief that healthcare providers and patients deserve the most current information available to make more informed decisions to improve outcomes. DNA Direct was the first genomics-focused company to offer URAC-accredited utilization management programs to help health plans in the appropriate use of genetic tests.

DynaMed is an evidence-based, clinical decision support tool that provides healthcare providers with the most useful information at the point of care. Every day, DynaMed editors monitor over 500 medical journals and evidence sources, evaluate new articles for clinical relevance and scientific validity, and provide ongoing synthesis of the best current evidence.  This process of Systematic Literature Surveillance, designed to provide the best available evidence to help answer clinical questions during practice, has also been found to be substantially helpful for guideline developers for evidence identification, critical appraisal, updating, and dissemination.

GenomOncology is enabling precision medicine by translating next generation sequencing data into actionable information for clinicians and researchers. In collaboration with molecular pathologists and physicians, GenomOncology has developed the GO Clinical WorkbenchTM, a decision support tool with a step-by-step workflow that takes raw data from the sequencer and translates the specific molecular profile of each patient’s tumor genome into an actionable clinical report.  More information can be found on the company’s website at

N-of-One interprets complex molecular diagnostic test results in oncology, linking results to therapeutic strategies supported by the most relevant clinical evidence for each patient. N-of-One has interpreted thousands of patient cases, enabling diagnostic labs and hospital systems to optimize time, quality and scalability. N-of-One leverages a leading team of scientists and oncologists propelled by state-of-the-art technology and N-of-One’s propriety database.

Navigating Cancer is the leading patient activation and engagement solution for cancer programs. For patients, Navigating Cancer provides a single, comprehensive hub that operates with any electronic health record vendor. This allows patients to stay informed and seamlessly engaged in their own care across multiple clinics, caregivers and geographies. For providers, Navigating Cancer offers a comprehensive platform of software and services for patient care and engagement, including an agile means of satisfying current requirements for Meaningful Use, Commission on Cancer and value-based payment reform models. For more information, visit


HIT tools that utilize the NCCN Compendium® as a reference

eviti is an innovative technology that offers providers oncology solutions through real-time access to evidence-based standards and intelligence at the point of clinical prescribing. eviti provides a comprehensive and unbiased digital library of evidence-based treatment regimens, taking into account cancer care costs, outcomes, efficacy and toxicities. In addition, it includes over 1,000 of the most appropriate, proven cancer treatment options covering all modalities for more than 120 cancer types, meticulously compiled from the world's leading sources.

HIT tools for patients and/or providers that utilize the NCCN Guidelines for Patients®


On Q Health offers care planning and clinical decision support technology that enables cancer clinicians to efficiently meet and document adherence to national quality standards. Our technology ensures clinicians deliver state-of-the-science care, encourages patient engagement and accountability, and improves clinician efficiency.


PatientsWithPower offers an online solution to help newly diagnosed breast cancer patients manage the overwhelming experience of an initial diagnosis, tackle the learning curve, and engage deeply in their own treatment planning. Our patient-centered service is an integrated communications platform for patients and their healthcare providers to discuss relevant medical options in the context of work, family and personal decision factors.

Mobile Applications that include NCCN Content

Epocrates, Inc. creates point-of-care digital solutions that enhance the practice of medicine. More than 1.4 million healthcare professionals, including 50% of U.S. physicians, use Epocrates to help improve patient care and practice efficiencies with its drug reference, educational, and clinical apps. For more information about Epocrates, please visit

Skyscape® is a leading provider of mobile apps for medical professionals, trusted by more than one million healthcare professionals worldwide. With more than 600 trusted resources covering 35 medical specialties, Skyscape enables physicians, nurses, students, and other healthcare professionals to provide quality patient care, save time and reduce costly medical errors. Unlike classic textbooks, Skyscape apps include advanced search, medical calculators, algorithms, and the ability to cross-reference multiple resources seamlessly, providing for optimal clinical decision support. Skyscape's unmatched breadth of trusted medical content is available for an array of devices, including iPhone, iPad, Android, and Blackberry. Skyscape is an official licensee of the NCCN Guidelines® to be utilized in mobile applications.

Utilization Management Companies which utilize NCCN Content


Oncology Analytics, Inc.


The NCCN is interested in working with organizations through permissions and licensing arrangements to permit the use of NCCN Content in commercial products. If you are interested in becoming a licensee of NCCN Content or if you want your HIT vendor to be a licensee, please contact C. Lyn Fitzgerald, Senior Vice President, U.S. and Global Development.