eBulletin Newsletter

NCCN Flash Updates: NCCN Templates Updated for Systemic Mastocytosis

NCCN has published updates to the NCCN Chemotherapy Order Templates (NCCN Templates®) for Systemic Mastocytosis and Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions to reflect the currently published NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Systemic Mastocytosis v3.2024 and Myeloid/Lymphoid Neoplasms with Eosinophilia and Tyrosine Kinase Gene Fusions v1.2024.

  • Changes to the Indication section have been made on the following NCCN Templates®:
    • MLNE5: Imatinib
  •  References have been updated on the following templates:
    • SM6: PEGinterferon alfa-2a
    • SM7: Avapritinib
    • MLNE12: Avapritinib
  • Changes to the Chemotherapy Regimen section have been made on the following templates:
    • SM2: Imatinib
    • MLNE1: Bosutinib
    • MLNE5: Imatinib
    • MLNE8: PONATinib
  • Drug information notes for the following agents have been updated in the Supportive Care, Monitoring and Hold Parameters, and/or Safety Parameters and Special Instructions sections:
    • Avapritinib
    • PONAtinib


For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Drugs & Biologics Compendium (NCCN Compendium®), the NCCN Biomarkers Compendium®, the NCCN Chemotherapy Order Templates (NCCN Templates®), the NCCN Radiation Therapy Compendium™, and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit NCCN.org.

To view the NCCN Guidelines for Patients®, please visit NCCN.org/patientguidelines.

Free NCCN Guidelines apps for iPhone, iPad, and Android devices are now available! Visit NCCN.org/apps.

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