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NCCN Flash Updates: NCCN Guidelines Updated for Adolescent and Young Adult Oncology

NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines^®) for Adolescent and Young Adult Oncology. These NCCN Guidelines^® are currently available as Version 2.2025.

Link directly to the Updates section of the NCCN Guidelines: Adolescent and Young Adult Oncology

AYAO-6

• Individuals with ovaries, bullet 4 modified: Discuss effects of treatment on gonadal hormone function during and after treatment. Some individuals face premature ovarian failure primary ovarian insufficiency and should be screened and treated by a specialist..."

AYAO-B 5 OF 6

• Bullet 1, sub-bullet 2 modified: "Impaired fertility (acute ovarian failure insufficiency or primary ovarian insufficiency): When marked depletion of the ovarian reserve occurs secondary to cancer therapy, ovarian insufficiency can develop soon after the completion of therapy. However, there may be a reproductive window before the onset of premature ovarian failure primary ovarian insufficiency..."

MS-1

• The discussion section has been updated to reflect changes in the algorithm.

For the complete updated versions of the NCCN Guidelines, NCCN Guidelines with NCCN Evidence Blocks™, the NCCN Drugs & Biologics Compendium (NCCN Compendium^®), the NCCN Biomarkers Compendium^®, the NCCN Chemotherapy Order Templates (NCCN Templates^®), the NCCN Radiation Therapy Compendium™, and the NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™), please visit NCCN.org.

To view the NCCN Guidelines for Patients^®, please visit NCCN.org/patientguidelines.

Free NCCN Guidelines apps for iPhone, iPad, and Android devices are now available! Visit NCCN.org/apps.

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NCCN Flash Updates™ is a subscription service from NCCN that provides timely notification of updated and new information appearing in the NCCN Guidelines, the NCCN Compendium^®, and other NCCN Content.

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