NCCN Shared Resources Database
NCCN recognizes the importance of the availability of and access to shared resources in conducting research. Such resources include complex technologies, instrumentation facilities, human tissue specimens, animal models and specialized databases. While each NCCN Member Institution has core resources, the number and types of resources vary from center to center. This database was established to enable our cancer centers to share their shared resources collectively as a means to make available to scientists and investigators resources that will improve the ability to conduct research and thereby facilitate scientific progress. New resources to advance cancer research will be added as they become available.
To use this website, you must be a registered user on the NCCN website using an institutional email address. Personal emails will not be able to access this secure website.
The Integrative Genomics Core at the City of Hope Comprehensive Cancer Center is pursuing the establishment of a Pacific Biosciences Sequencing service which would be made available to our NCCN partners. The PacBioRSII system uses the Single Molecule Real Time (SMRT) technology to achieve results not possible with other platforms, such as average read lengths in excess of >10 kb with >99.999% consensus accuracy. RNA can be sequenced directly, allowing for analysis of splice site variation without the need for read assembly; GC and AT rich repeat expansions can be read with minimal bias reducing exome gaps, compound mutations linked by hundreds or even thousands of bases can be identified, SNP detection and validation can be achieved with higher accuracy, reducing the rate of false positives/negatives, and base modifications such as methylation can be detected directly without the need for chemical modification. This technology offers a unique opportunity for new discoveries in cancer genomics and collaboration within the NCCN. City of Hope and PacBio will provide $50,000 in funds to initiate up to 10 new projects once the center is established. This will be open to PIs within the NCCN. Additional details will follow once the service is up and running. Please contact John Termini at firstname.lastname@example.org to express your interest or for any questions and additional information.