National Comprehensive Cancer Network

The NCCN Guidelines are copyrighted by the NCCN. All rights reserved. NCCN Guidelines and illustrations (including algorithms) may not be reproduced in any form for any purpose without the express written permission of the NCCN. Permissions Requests Section.

Click here to view the NCCN Guidelines Panel Members individual disclosures

NCCN Guidelines for Treatment of Cancer by Site

NCCN Guidelines for Detection, Prevention, & Risk Reduction

NCCN Guidelines for Supportive Care

NCCN Guidelines for Specific Populations

NCCN Guidelines for Patients

The NCCN guidelines are FREE! Register for a free account, then click on the cancer types below to display a drop down of options. If you are still having an issue, please contact us.

If you can see this message there appears to be an issue with the javascript in your browser. Please click here to view the NCCN Guidelines without javascript.

NCCN GUIDELINES FOR TREATMENT OF CANCER BY SITE

Acute Lymphoblastic Leukemia

Acute Myeloid Leukemia

AIDS-Related Kaposi Sarcoma

Anal Carcinoma

Basal Cell Skin Cancer (See Non-Melanoma Skin Cancers)

Bladder Cancer

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Bladder Cancer
Upper Tract Tumors
Urothelial Carcinoma of the Prostate
Primary Carcinoma of the Urethra
NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™)
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

Bone Cancer

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Chondrosarcoma
Chordoma
Ewing's Sarcoma Family of Tumors
Giant Cell Tumor of the Bone
Osteosarcoma

Breast Cancer

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Noninvasive
Invasive
Phyllodes Tumor
Paget's Disease
Breast Cancer During Pregnancy
Inflammatory Breast Cancer
NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™)
NCCN Guidelines for Patients (Noninvasive Breast Cancer)
NCCN Guidelines for Patients (Invasive Breast Cancer)
NCCN Guidelines for Patients (Metastatic Breast Cancer)
NCCN QUICK GUIDE™ sheet for Noninvasive Breast Cancer
NCCN QUICK GUIDE™ sheet for Invasive Breast Cancer
NCCN QUICK GUIDE™ sheet for Metastatic Breast Cancer
Patient Resources - Know What Your Doctors Know: Metastatic Breast Cancer
NCCN Educational Events and Programs
NCCN 2019 Congress Series™: Breast Cancer with Updates from 2018 San Antonio Breast Cancer Symposium
NCCN International Translations/Adaptations

Cancer of Unknown Primary (See Occult Primary)

Central Nervous System Cancers

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Adult Low-Grade Infiltrative Supratentorial Astrocytoma/Oligodendroglioma (excluding pilocytic astrocytoma)
Anaplastic Gliomas/Glioblastoma
Adult Intracranial Ependymoma
Adult Medulloblastoma
Primary CNS Lymphoma
Primary Spinal Cord Tumors
Meningiomas
Limited Brain Metastases
Extensive Brain Metastases
Leptomeningeal Metastases
Metastatic Spine Tumors
NCCN Educational Events and Programs

Cervical Cancer

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Myeloid Leukemia

Colon/Rectal Cancer

Colon Cancer

Rectal Cancer

Cutaneous Melanoma (See Melanoma)

Dermatofibrosarcoma Protuberans (See Non-Melanoma Skin Cancers)

Endometrial Cancer (See Uterine Neoplasms)

Esophageal and Esophagogastric Junction Cancers

Fallopian Tube Cancer (See Ovarian Cancer)

Gastric Cancer

Gestational Trophoblastic Neoplasia

Hairy Cell Leukemia

Head and Neck Cancers

NCCN Guidelines with NCCN Evidence Blocks^™ – Very Advanced Head and Neck Cancer – About NCCN Evidence Blocks^™
NCCN Guidelines
Cancer of the Lip
Cancer of the Oral Cavity
Cancer of the Oropharynx
Cancer of the Hypopharynx
Cancer of the Nasopharynx
Cancer of the Glottic Larynx
Cancer of the Supraglottic Larynx
Ethmoid Sinus Tumors
Maxillary Sinus Tumors
Very Advanced Head and Neck Cancers
Occult Primary
Salivary Gland Tumors
Mucosal Melanoma
NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™) – Cancers of the Lip and Oral Cavity
NCCN Guidelines for Patients
NCCN QUICK GUIDE™ sheet for Oral Cancers
NCCN Educational Events and Programs

Hepatobiliary Cancers

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Hepatocellular Carcinoma
Biliary Tract Cancers

Gallbladder Cancer
Intrahepatic Cholangiocarcinoma
Extrahepatic Cholangiocarcinoma

NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™) – Hepatocellular Carcinoma and Gallbladder Cancer
NCCN Guidelines for Patients
NCCN QUICK GUIDE™ for Hepatobiliary Cancers
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

Hodgkin Lymphoma

Kidney Cancer

Malignant Pleural Mesothelioma

Melanoma

Cutaneous Melanoma

Uveal Melanoma

NCCN Guidelines

Merkel Cell Carcinoma (See Non-Melanoma Skin Cancers)

Multiple Myeloma/Other Plasma Cell Neoplasms

Multiple Myeloma

Systemic Light Chain Amyloidosis

Waldenström's Macroglobulinemia / Lymphoplasmacytic Lymphoma

Myelodysplastic Syndromes

Myeloproliferative Neoplasms

Neuroendocrine and Adrenal Tumors

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Neuroendocrine Tumors of the GI, Lung and Thymus (Carcinoid Tumors)
Neuroendocrine Tumors of the Pancreas
Neuroendocrine Unknown Primary
Adrenal Gland Tumors
Pheochromocytoma/Paraganglioma
Poorly Differentiated (High Grade or Anaplastic)/Small Cell
Multiple Endocrine Neoplasia, Type 1
Multiple Endocrine Neoplasia, Type 2
NCCN Guidelines for Patients
NCCN QUICK GUIDE™
NCCN Educational Events and Programs

Non-Hodgkin's Lymphomas

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (See Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma)

B-Cell Lymphomas

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Follicular Lymphoma
Marginal Zone Lymphomas

Gastric MALT Lymphoma
Nongastric MALT Lymphoma
Nodal Marginal Zone Lymphoma
Splenic Marginal Zone Lymphoma

Mantle Cell Lymphoma
Diffuse Large B-Cell Lymphoma
High-Grade B-Cell Lymphomas

High-Grade B-Cell Lymphomas with Translocations of MYC and BCL2 and/or BCL6 (Double/Triple Hit Lymphoma)
High-Grade B-Cell Lymphomas, NOS

Burkitt Lymphoma
AIDS-Related B-Cell Lymphomas
Lymphoblastic Lymphoma
Post-Transplant Lymphoproliferative Disorders
Castleman's Disease
NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™) – Diffuse Large B-cell Lymphoma and Burkitt Lymphoma
- Basic Resources
- Core Resources
- Enhanced Resources
NCCN Guidelines for Patients - Diffuse Large B-Cell Lymphoma
NCCN Guidelines for Patients - Follicular Lymphoma
NCCN Guidelines for Patients - Mantle Cell Lymphoma
NCCN QUICK GUIDE™ sheet for Diffuse Large B-Cell Lymphoma
NCCN QUICK GUIDE™ sheet for Follicular Lymphoma
NCCN QUICK GUIDE™ sheet for Mantle Cell Lymphoma
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

Hairy Cell Leukemia (See Hairy Cell Leukemia)

Primary Cutaneous Lymphomas

NCCN Guidelines
Primary Cutaneous B-Cell Lymphomas
Mycosis Fungoides/Sézary Syndrome
Primary Cutaneous CD30+ T-Cell Lymphoproliferative Disorders
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

T-Cell Lymphomas

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Peripheral T-Cell Lymphoma, Noncutaneous
Breast Implant-Associated Anaplastic Large Cell Lymphoma (ALCL)
T-cell Large Granular Lymphocytic Leukemia
Adult T-Cell Leukemia/Lymphoma
T-Cell Prolymphocytic Leukemia
Extranodal NK/T-Cell Lymphoma, nasal type
Hepatosplenic Gamma-Delta T-cell Lymphoma
NCCN Guidelines for Patients - Mycosis Fungoides
NCCN Guidelines for Patients - Peripheral T-cell Lymphoma
NCCN QUICK GUIDE™ sheet for Mycosis Fungoides
NCCN QUICK GUIDE™ sheet for Peripheral T-cell Lymphoma
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

Non-Melanoma Skin Cancers

Basal Cell Skin Cancer

Dermatofibrosarcoma Protuberans

Merkel Cell Carcinoma

Squamous Cell Skin Cancer

Non-Small Cell Lung Cancer

Occult Primary

Ovarian Cancer

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Epithelial Ovarian Cancer (including Fallopian Tube Cancer and Primary Peritoneal Cancer)
Borderline Epithelial Ovarian Cancer (Low Malignant Potential)
Less Common Ovarian Histologies
NCCN Guidelines for Patients
NCCN QUICK GUIDE™ for Ovarian Cancer – Treatment Planning
NCCN QUICK GUIDE™ for Ovarian Cancer – Treatment Options
NCCN Educational Events and Programs
NCCN International Translations/Adaptations

Pancreatic Adenocarcinoma

Penile Cancer

Primary Peritoneal Cancer (See Ovarian Cancer)

Prostate Cancer

Small Cell Lung Cancer

Soft Tissue Sarcoma

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Extremity
Retroperitoneal/Intra-Abdominal
Gastrointestinal Stromal Tumors (GIST)
Desmoid Tumors
Rhabdomyosarcoma
NCCN Guidelines for Patients
NCCN Educational Events and Programs

Squamous Cell Skin Cancer (See Non-Melanoma Skin Cancers)

Systemic Mastocytosis

Testicular Cancer

Thymomas and Thymic Carcinomas

Thyroid Carcinoma

NCCN Guidelines with NCCN Evidence Blocks^™ – About NCCN Evidence Blocks^™
NCCN Guidelines
Nodule Evaluation
Papillary Carcinoma
Follicular Carcinoma
Hürthle Cell Neoplasm
Medullary Carcinoma
Anaplastic Carcinoma
NCCN Guidelines for Patients

Uterine Neoplasms

Vulvar Cancer

NCCN GUIDELINES FOR DETECTION, PREVENTION, & RISK REDUCTION

Breast Cancer

Breast Cancer Risk Reduction

Breast Cancer Screening and Diagnosis

NCCN Guidelines
NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™)
- Basic Resources (Preliminary)
- Core Resources (Preliminary)
- Enhanced Resources (Preliminary)

Genetic/Familial High-Risk Assessment: Breast and Ovarian

NCCN Guidelines
Breast and/or Ovarian Genetic Assessment
Hereditary Breast and/or Ovarian Cancer
Li-Fraumeni Syndrome
Cowden Syndrome
NCCN International Translations/Adaptations

Cervical Cancer Screening

The NCCN Guidelines Panel for Cervical Cancer Screening endorses the following guidelines:

For the prevention and early detection of cervical cancer: American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer. Am J Clin Pathol 2012;137:516-542. Available at: https://doi.org/10.1309/AJCPTGD94EVRSJCG
For the management of abnormal cervical screening tests and cancer precursors: 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. J Low Genit Tract Dis 2013;17(5 Suppl 1):S1-S27. Available at: http://www.asccp.org/

Colorectal Cancer

Colorectal Cancer Screening

Genetic/Familial High-Risk Assessment: Colorectal

NCCN Guidelines

Lung Cancer Screening

Prostate Cancer Early Detection

NCCN GUIDELINES FOR SUPPORTIVE CARE

Adult Cancer Pain

Antiemesis

NCCN Guidelines

Cancer- and Chemotherapy-Induced Anemia

NCCN Guidelines

Cancer-Associated Venous Thromboembolic Disease

NCCN Guidelines

Cancer-Related Fatigue

NCCN Guidelines

Distress Management

Management of Immunotherapy-Related Toxicities

NCCN Guidelines
Immune Checkpoint-Inhibitor Toxicities
CAR T-Cell-Related Toxicities

Myeloid Growth Factors

Palliative Care

Prevention and Treatment of Cancer-Related Infections

NCCN Guidelines

Smoking Cessation

NCCN Guidelines

Survivorship

NCCN Guidelines
Late Effects/Long-Term Psychosocial and Physical Problems
- Anthracycline-Induced Cardiac Toxicity
- Anxiety and Depression
- Cognitive Function
- Fatigue
- Lymphedema
- Menopause-Related Symptoms
- Pain
- Sexual Function (female/male)
- Sleep Disorders
Preventive Health

Healthy Lifestyles

Physical Activity
Nutrition and Weight Management
Supplement Use

Immunizations and Infections

NCCN GUIDELINES FOR SPECIFIC POPULATIONS

Adolescent and Young Adult (AYA) Oncology

Cancer in People Living with HIV

NCCN Guidelines

Older Adult Oncology

NCCN Guidelines

Disclaimer
The NCCN Guidelines are a statement of consensus of the authors regarding their views of currently accepted approaches to cancer treatment. The recommendations regarding the uses and indications in the NCCN Compendium have been derived directly from the NCCN Guidelines. The NCCN Compendium represents neither an all-inclusive listing of every drug and biologic nor every appropriate use and indication for drugs and biologics. The NCCN Templates are peer reviewed statements of consensus of their authors derived from the NCCN Guidelines for the conditions the NCCN Templates address. The NCCN Templates are not exhaustive and do not represent the full spectrum of care or treatment options described in the NCCN Guidelines or the NCCN Compendium or include all appropriate approaches or combinations of drugs or biologics for the treatment of cancer. A NCCN Template does not constitute an order.

Web Citation for NCCN Guidelines

Help with Viewing the NCCN Guidelines

Please note that the guidelines listed are Acrobat PDF files. To view these files the Acrobat Reader plug-in must be installed in your browser. Click here for further instructions and a link to the free download site if needed.

Please maximize your browser window to view these guidelines. Please note that there may be a delay of several seconds to a minute or more, depending on the speed of your connection, as the PDFs download into your browser window.